Two geo-referenced datasets with carbon and nitrogen isotopic values of Procambarus clarkii in invaded inland waters resolved respectively at population- and individual-scale. The population-scale dataset consists of 160 δ13C and δ15N isotopic values of P. clarkii and its potential prey, including living and non-living primary producers and benthic invertebrates. The individual-scale dataset consists of 1,168 isotopic individual records of P. clarkii. The isotopic information included within the two datasets was gathered from 10 countries located in Europe, Asia, Africa, and North America, and from a total of 41 studies published between 2005 and 2021.

This dataset includes 1,998 records with distribution and abundance information of the invasive species Anadara kagoshimensis and A. transversa. Sample collection occurred at 66 trawling stations located in the Italian waters of the Northern Adriatic Sea within the framework of the SoleMon project (CNR-IRBIM) between 2008 and 2023. The dataset was compiled, harmonised and published within the CNR project USEit - Using operational synergies for the study and integrated management of invasive alien species in Italy.